Soooo, after watching 300 runs of the game by Northernlion, I finally understood it was my fate to play this game now that rebirth is out. You can discuss about your discoveries, tell us about the most stupid builds you got, post run videos, synergies that are completely overpowered, etc. On my part, I just did 3 runs aaand I'm the luckiest ever : 1st run : technlogy (slowish pew pew laser), soap (way less damage but CRAZY rate of fire), pentagram (more damage), and libra, that gives 6 keys/6 bombs/6 coins and seems to balance your stats. So I ended up with a normal fire rate again, counter-balanced with gigantic DPS considering I only got pentagram as a damage upgrade. Killed mom in 15 seconds. 2nd run, Cain : thunder thighs, mulligan, phd, guppy paw+soul converter combo (INFINITE HEALTH as long as you have access to the room where you left one of the two and keep the other one with you) so I had 8 red hearts and guppy paw for difficult situations, blood clot (damage and range), 5 tears up pills, mom's eye with luck up pills so I got the both-way shot at every shot, pact (fire rate and damage), 3 range up pills, 3 pretty fly pills. Killed mom's heart without moving an inch, was so easy I gave the normal ending the middle finger and went in hell to headbutt Satan directly. 3rd run, lazarus :... Infestation 2 (spawns a friendly spider for every kill you get with your own tears), dark bum (gathers lying red hearts and gives you soul hearts with a 2/3 rate), bum friend (takes lying coins and gives you every kind of consumables), Leo (you break rocks and poop by just walking into them, and the thing that made it absolutely bullshit : lucky rock trincket, that makes every destroyed rock drop 1 penny. which makes that kind of thing possible in every room with plenty of rocks : Spoiler (Move your mouse to the spoiler area to reveal the content) Show Spoiler Hide Spoiler Who got better?